magickpencil: Per usual, this is all anecdotal ; don't take SWIM's word for it--SWIM is taking SWIS's word for it!
Regardless, this an interesting read
You'll find the source here: The DMT-Nexus Ľ 69Ron's "Triple E" Tech for Elemicin Extraction from Elemi Oil
Originally Posted by 69ronEDIT: DMSO INTRODUCES PROBLEMS WITH ELEMICIN DIGESTION AND NEGATIVELY AFFECTS THE EXPERIENCE. TO SOLVE THIS ISSUE WITH THE TECH, BEFORE USE ALWAYS DILUTE THE FINAL EXTRACT AS STATED BELOW.
There are a few extraction techs available on the net. Hereís one that is all over the place:
While good to know, itís not practical for most people.Elemicin (4-allyl-l,2,6-trimethoxy benzene), C12H1603, constitutes the principal constituent of Manila elemi oil, in which it was discovered by Semmler1) who also gave it its name. It is found in fraction 277 to 280į of elemi oil.2) In order to isolate elemicin, the fraction in question is boiled for half an hour with formic acid. As Semmler has demonstrated by experiments made on anethol and safrol, allyl compounds remain unchanged, whereas propenyl compounds are destroyed.
SWIM did a test last night, and seems to have stumbled upon a simpler kitchen tech for concentrating the elemicin found in Elemi oil.
Here are the steps for 1 dose (0.5 ml, or about 18 drops).
69Ron's "Triple E" Tech for Elemicin Extraction from Elemi
1 - measure out 0.5 ml of 100% pure therapeutic grade Elemi essential oil and put in a small micro beaker (or any other suitable container).
2 - measure out 2.5 ml of the standard DMSO available at the health food stores (this DMSO is 99.9% pure DMSO mixed with 30% water, so itís actually 70% DMSO) and add it to the Elemi oil.
3 - Mix the two liquids thoroughly for about 1 minute. Then let it sit for a few seconds. After a while the two liquids separate into two distinct layers. The clear bottom layer contains most of the elemicin. The sedative compound and a bunch of other junk in the Elemi oil remains in the top yellowish layer. NOTE: Before mixing, the top Elemi oil layer is yellowish and glows greenish blue in UV light while the bottom DMSO layer is clear and doesn't glow in UV light. But after mixing and settling, the top yellowish layer no longer glows in UV light, but instead the bottom clear DMSO layer glows greenish blue in UV light, indicating one or more components have almost completely migrated into the bottom DMSO layer.
4 - Separate the top yellowish layer from the clear bottom layer and discard the top yellowish layer. The clear bottom layer is your end product containing the elemicin. An easy way to separate the layers is by using a 5 ml glass pipette. A standard separatory funnel is simply too large to use for this. A micro separatory funnel would be fine, but honestly a pipette works very well. You could even use an HDPE plastic pipette for this.
Simply drink the DMSO DILUTED IN 1 CUP OF MILK or some other liquid.
Don't take the DMSO directly. If taken directly, the effects of the elemcin will be inferior, far less psychedelic, less euphoric, and it will have more stimulant effects, and may cause muscle tension in some people. It needs to be diluted. The more, the better. Apparently DMSO causes a lot of the elemicin to soak into your flesh and bypass the digestive system. It seems to be necessary for elemicin to be digested properly in order get its LSD-like effects. There is a theory that elemicin is aminated to TMA when properly digested. Concentrated DMSO would prevent this from happening to a good portion of the elemicin. While it's just a theory that elemicin is aminated to TMA in the digestive system, tests done by several of SWIM's friends seem to indicate that something like this is happening. So don't use the DMSO directly. Always dilute it before use.
After extracting the elemi oil into the DMSO, the foggy sedated withdrawn feeling of whole Elemi oil had at large doses is no longer present. Only the desired psychedelic elemicin seems to be active in the DMSO layer. But remember to dilute the DMSO prior to use.
5ml DMSO & 1ml elemi oil before separation (super macro) // Image by q21q21 / source
How does this tech work?
If we look at the XLogP data for the various compounds found in Elemi essential oil, we can see that elemicin has a very low XLogP and should be soluble in DMSO, while a vast majority of the other compounds present in large amounts have a high XLogP value and will not be soluble in DMSO.
Compounts in Elemi oil likely soluble in DMSO:Compounts in Elemi oil likely insoluble in DMSO:Code:00.2% Carvone XLogP3-AA 2.4 00.3% Methyl eugenol XLogP3 2.5 03.5% Elemicin XLogP3 2.5 02.5% 1,8-Cineole (Eucalyptol) XLogP3 2.5 00.6% Terpinolene XLogP3-AA 2.8 00.4% gamma-Terpinene XLogP3-AA 2.8 00.4% alpha-Pinene XLogP3-AA 2.8Everything with an XLogP of 3.2 and up seems to be insoluble in DMSO. Since this is the majority of the oil, most of the oil is removed. Only about 5-10% of the oil remains in the DMSO. How much remains in the DMSO after mixing will depend on the oil used. Oil with a high elemicin content will lose a larger percentage to the DMSO.Code:15.1% alpha-Phellandrene XLogP3-AA 3.2 54.1% Limonene XLogP3-AA 3.4 00.8% beta-Phellandrene XLogP3-AA 3.4 01.5% para-Cymene XLogP3 4.1 02.4% Myrcene XLogP3-AA 4.3 15.0% Elemol XLogP3-AA 4.4
The myrcene which is removed by this tech is very likely the main sedative component of the oil. Myrcene is the main active compound of lemongrass. The data shows that it should be active as a sedative in Elemi oil in doses as low as 14 drops. Because of myrceneís high XLogP, it is insoluble in DMSO. The other compounds removed including limonene, alpha-phellandrene, beta-phellandrene, para-cymene, and elemol are most likely to be inactive at the dosage range present in 10-20 drops of elemi oil. I feel confident that myrcene is the compenent responsible for most of the sedation felt in Elemi oil doses above 12 drops. Itís the only sedative compound present in Elemi oil that I know is active at such a small doses.
While the extract produced by this tech is not pure elemicin, itís effects are dramatically cleaner than whole Elemi oil. Very few of the compounds soluble in DMSO are active at the small amounts present. Elemicin is apparently very potent, being the most active compound in whole Elemi oil, despite it being present in pretty small amounts. By removing the non DMSO soluble compounds, we effectively remove about 90-95% of the oil, leaving elemicin and eucalyptol (1,8-cineole) in the DMSO as the primary compounds. With eucalyptol being many times less potent than elemicin, its effects are virtual absent from the experience had from using the DMSO. For eucalyptol to be an effective sedative you need about 2 ml of it. With Elemi oil containing only about 2.5% eucalyptol, youíd need 80 ml of Elemi oil to get an effect from the eucalyptol in it, while you need only 0.1-0.5 ml of Elemi oil to get an effect from the elemicin. So clearly the eucalyptol present in the DMSO is not going to do anything at doses high enough to get a decent elemicin trip.
Eucalyptol Contamination Causing Sedation in the End Product?
The main sedative in the oil is myrcene, but this is removed by this tech. If your Triple E extract is still sedating, itís very likely contaminated with a lot of eucalyptol. After doing some research, I found that some elemi oil is pretty high in eucalyptol. Eucalyptol will be extracted along with elemicin using this tech. It is difficult to remove it.
Like myrcene, eucalyptol will interfere with the psychedelic effects of elemicin, and some people are apparently very sensitive to the effects of eucalyptol, only needing a drop to feel it!
Eucalyptol has the following actions: antiseptic, antispasmodic, depressant, expectorant.
Side effects from eucalyptol include: headache, lightheadedness, sedation, respiratory depression, vomiting, drop in blood pressure, circulation problems, collapse, and asphyxiation.
Eucalyptol is something you donít want to ingest in high amounts. If your end product is still sedating, itís most likely contaminated with lots of eucalyptol, or you are very sensitive to eucalyptol. My advice, donít up the dose if you feel sedation. Find a different source of elemi oil, one that is high in elemicin and low in eucalyptol. Elemi oil that is high in elemicin smells like nutmeg and roses. The end product of this extract should smell strongly of nutmeg.
Does this work with nutmeg oil?
SWIM has not tried this with nutmeg oil. It may possibly help cleanup the nutmeg oil experience. However the XLogP3 of myristicin is 2.9, so it might not get all of the myristicin out of the oil. It would however get most of the elemicin out (it has an XLogP3 of 2.5 so itís more soluble in DMSO).